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A Histopathologic and Histochemical Investigation

RICHARD K. WINKELMANN, M.D.; HAMILTON MONTGOMERY, M.D.

AMA Arch Derm. 1956;74(1):63-68.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The clinical features of Fox-Fordyce disease constitute a distinct picture. The findings of a symmetric eruption of discrete, flesh-colored to pink papules oriented about the follicular openings with intervening normal skin and located in the axillae and about the external genitalia, the areolae, and the umbilicus, together with the overwhelming predominance in sexually active females and with the exquisite pruritus which accompanies it, distinguish this condition clearly. Difficulties arise only when secondary infection or sensitization, miliaria or lichenification occurs. The clinical features have been excellently reviewed by Goodman¹ and Chatellier.²

By contrast, the etiologic and histopathologic picture in this condition is not well defined. The process was originally considered a form of localized neurodermatitis by the authors who described it.³ However, Gougerot and co-workers^* described a type without pruritus. Since the work of Schiefferdecker on the apocrine glands, most authors have . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn.

Footnotes
Received for publication Aug. 11, 1955.

Fellow in Dermatology, Mayo Foundation (Dr. Winkelmann); Section of Dermatology, Mayo Clinic and Mayo Foundation (Dr. Montgomery). The Mayo Foundation is a part of the Graduate School of the University of Minnesota.

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