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JOHN van de ERVE, Jr.

AMA Arch Derm. 1956;74(1):92-94.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A clinical study of 335 cases of dermatitis treated with hydrocortisone and fludrocortisone (9-fluorohydrocortisone) applied topically in both lotion and ointment form by the method of paired comparisons was begun Sept. 28, 1954, and is still being continued. Fludrocortisone was supplied for this study in strengths of 0.1% and 0.25% in lotion form in oz. (15 cc.) plastic bottles and in strengths of 0.1%, 0.25%, and 0.5% in ointment form. Corresponding strengths of 1% and 2.5% hydrocortisone in identical vehicles were used for paired comparison with the fludrocortisone preparations. The vehicles were also supplied in similar containers for placebo comparison.

Method

Patients with selected dermatoses in private office practice were given pairs of the corticoid preparations, the fludrocortisone being 1/10 as strong as the hydrocortisone. They were instructed to apply the lotion or ointment thrice daily to the affected areas. In most cases simultaneous contralateral applications were . . . [Full Text PDF of this Article]

Author Affiliations
Charleston, S. C.

From Department Dermatology, Medical College of South Carolina, (Dr. van de Erve, Clinical Professor Dermatology).

Footnotes
Submitted for publication May 18, 1955.

Fludrocortisone and Hydrocortisone supplied by courtesy of Dr. S. Clyde Strickland, Sharp & Dohme Medical Division, West Point, Pa.

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