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II. Results of Therapy as Measured by Laboratory Findings

RICHARD D. HAHN, M.D.; JOHN C. CUTLER, M.D.; ARTHUR C. CURTIS, M.D.; GEORGE GAMMON, M.D.; ALBERT HEYMAN, M.D.; EDGAR JOHNWICK, M.D.; JOHN H. STOKES, M.D.; HARRY SOLOMON, M.D.; EVAN THOMAS, M.D.; WILLIAM TIMBERLAKE, M.D.; BRUCE WEBSTER, M.D.; GERALDINE A. GLEESON, A.B.

AMA Arch Derm. 1956;74(4):367-377.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During the past several years, the Venereal Disease Program, in cooperation with a number of well-known clinics and hospitals throughout the country, has conducted a study to determine the effectiveness of penicillin in the treatment of asymptomatic neurosyphilis. A preceding report¹ has shown that factors such as age, race, sex, previous treatment, and re-treatment status have little or no relationship to clinical prognosis in penicillin-treated asymptomatic central nervous system (CNS) syphilis. The present report deals with the pretreatment and post-treatment status of the patient group in terms of results of blood and spinal fluid examinations.

This study consists of 765 patients with asymptomatic neurosyphilis, whose histories were selected from the records of eight cooperating clinics in accordance with the following criteria: (1) reactive spinal fluid, i.e., abnormalities in the spinal fluid test for syphilis, colloidal test, total protein, or cell count, or . . . [Full Text PDF of this Article]

Author Affiliations
Baltimore; Washington, D. C.; Ann Arbor, Mich.; Philadelphia; Atlanta; Hot Springs, Ark.; Philadelphia; Boston; New York; Boston; New York; Washington, D. C.

Footnotes
Submitted for publication Sept. 14, 1955.

Report of the Cooperative Clinical Group, U. S. Public Health Service, with statistical analyses by the Office of Statistics, Venereal Disease Program, Division of Special Health Services, United States Public Health Service, Washington, D. C.

Expanded reprints of these papers are available upon request to the Chief, Venereal Disease Program, Division of Special Health Services, Public Health Service, U. S. Department of Health, Education, and Welfare, Washington 25, D. C.

Johns Hopkins Hospital (Dr. Hahn); Medical Director, U. S. Public Health Service (Dr. Cutler); University of Michigan (Dr. Curtis); University of Pennsylvania (Drs. Gammon and Stokes); Emory University School of Medicine (Dr. Heyman); Hot Springs Medical Center (Dr. Johnwick); Boston Psychopathic Hospital (Drs. Solomon and Timberlake); Bellevue Hospital (Dr. Thomas); New York Hospital (Dr. Webster); Statistician, U. S. Public Health, Service (Mrs. Gleeson).

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