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Reaction from Hydrocortisone Suspension Vehicle (Sodium Carboxymethyl Cellulose)

A. B. LOVEMAN, M.D.; M. T. FLIEGELMAN, M.D.

AMA Arch Derm. 1956;74(4):426.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

One case of allergic urticaria has been reported resulting from sensitivity to the suspending agents in the aqueous vehicle of hydrocortisone suspension.^* The specific incriminating allergen apparently was not determined.

To our knowledge, therefore, the following case is the first to be reported in which a specific component of the hydrocortisone vehicle has been shown to provoke a systemic cutaneous allergic reaction.

Report of a Case

A white woman, aged 47, was seen in our office on Sept. 2, 1954, at which time 0.2 cc. of hydrocortisone (Merck's Hydrocortone suspension) was injected into and beneath a synovial cyst of the right fourth finger. Several additional injections were made at two- to three-week intervals, and, according to the patient, after each injection, with the exception of the first, she experienced an extensive hemorrhagic eruption.

We were able to reproduce the eruption . . . [Full Text PDF of this Article]

Author Affiliations
Louisville

Footnotes
Recorded for publication Nov. 9, 1955.

Studies and Contributions from the Section of Dermatology and Syphilology, Department of Medicine, University of Louisville School of Medicine.

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