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Treatment of Cutaneous Fungus Infections with a Phenylsalicylamide Derivative
FRANCES KEDDIE, M.D.;
GEORGE F. HEXTER, M.D.;
ALCOR S. BROWN, Ph.D.
AMA Arch Derm. 1956;74(5):504-510.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Introduction
Successful control of cutaneous dermatophytosis usually requires the judicious use of fungicidal agents. During the last war several effective compounds came into use as a result of extensive investigation conducted by the Armed Services.9 The best of these proved to be undecylenic acid. Unfortunately neither the newer agents nor various combinations of old and recent remedies are effective in all or even in a majority of patients with fungus infections of the skin. Furthermore some of these agents induce sensitivity reactions which complicate treatment. For these reasons a further study of fungicidal agents has been undertaken. The purpose of this study is to report the clinical results obtained in the treatment of a group of 159 patients treated with a new fungicide.1 The results have been sufficiently successful to encourage wider study of this drug.
Materials and Methods
The compound under study is N-n-butyl-3-phenylsalicylamide*: It
. . . [Full Text PDF of this Article]
Author Affiliations
Palo Alto, Calif.; Long Beach, Calif.; Berkeley, Calif.
From the Palo Alto Medical Research Foundation, Palo Alto Medical Clinic, Palo Alto, Calif., and State of California Department of Public Health, Berkeley, Calif.
Footnotes
Submitted for publication Jan. 13, 1956.
Aided by grant from Cutter Laboratories, Berkeley, Calif.
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