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  Vol. 74 No. 5, November 1956 TABLE OF CONTENTS
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Pyoderma Gangrenosum

Report of a Case Controlled by Cortisone

EDWIN T. WRIGHT, M.D.; DONALD J. GRECO, M.D.

AMA Arch Derm. 1956;74(5):543-546.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Chronic undermining burrowing ulcers which spread peripherally and are characteristically resistant to treatment have been described under several titles, such as, pyoderma gangrenosum,1 hemolytic streptococcus gangrene,2 progressive bacterial synergistic gangrene,3 and necrotizing fasciitis.4 These ulcers have developed following surgical wounds, abrasions, contusions, lacerations, insect bites, and gunshot wounds.4 They have also been observed to occur in association with ulcerative colitis.1

The combination of a microaerophilic nonhemolytic Streptococcus with a hemolytic Staphylococcus aureus was first demonstrated to be the etiological agents by Brewer and Meleney.5 Several other organisms have also been found in these ulcers. Meleney, Friedman, and Harvey3 demonstrated the presence of a penicillinase-producing Pseudomonas aeruginosa and Escherichia coli on one occasion. Lyall and Stuart6 isolated a microaerophilic Streptococcus with a Proteus vulgaris in one case. Other investigators* have also . . . [Full Text PDF of this Article]


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