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The Histopathological Picture of a Cutaneous Lesion: Report of a Case

MAJOR CHARLES S LINCOLN, Jr.

AMA Arch Derm. 1957;75(1):107-111.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A bizarre condition involving tissue changes in the respiratory tract, kidneys, and spleen was first described by Klinger¹ in 1931. Subsequently the disease syndrome or a very similar syndrome consisting of extravascular granulomas and a generalized periarteritis nodosa has been described under a multiplicity of titles, the most commonly accepted being Wegener's granulomatosis² and allergic granulomatosis.^3,4 More recently, in 1955, Fienberg⁵ suggested pathergic granulomatosis as the best term on the basis of pathogenesis. Pathergy as defined by Rössle⁶ is a condition in which the application of a stimulus leaves the organism in a state in which it is unduly susceptible to subsequent stimuli of a different kind. Fienberg⁵ further proposed that this condition be divided into two varieties: (1) disseminated pathergic granulomatosis, and (2) a focal variety in which only a single organ or a portion of an organ is . . . [Full Text PDF of this Article]

Author Affiliations
(MC), U. S. Army Reserve

Footnotes
Submitted for publication May 8, 1956.

Dr. Lincoln's present address is 1300 Bancroft Ave., San Leandro, Calif.

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