This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Their Interrelations

ADOLPH ROSTENBERG, Jr., M.D.

AMA Arch Derm. 1957;75(4):547-558.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

It is well known that eczematous skin reactions can be produced either by a primarily irritating substance or by an allergen. It will be the purpose of this paper to discuss the nature of the two types of eczematous reactions and their interrelations.

An eczematous allergen is defined as a substance that is not primarily irritating on first exposure but which, in persons of the appropriate genetic constitution, causes the development of an allergic sensitization of the delayed type, so that subsequent contact with concentrations that are nonirritating to unexposed or nonsensitized persons produces an eczematous reaction. A primary eczematous irritant is defined as a substance which produces an eczematous response by nonimmunologic means. Primary irritants may be divided into two categories: (1) immediate, and (2) cumulative. An immediate primary irritant is the usual type. Here the eczematous reaction is produced on first exposure. The . . . [Full Text PDF of this Article]

Author Affiliations
Chicago

From the Department of Dermatology, University of Illinois College of Medicine.

Footnotes
Received for publication July 12, 1956.

A review of the literature preliminary to studies in progress being supported by U. S. Public Health Service Grant RG-4415.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?