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FREDERICK URBACH, M.D.; EUGENE M. BURKE, B.S.; HERBERT L. TRAENKLE, M.D.

AMA Arch Derm. 1957;76(3):343-350.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Cytologic methods for the diagnosis of cancer have been utilized in various ways at least since 1867.¹ Since 1943, when Papanicolaou and Traut wrote a monograph on exfoliative cytology, modifications of their method have been applied to most body areas where secretions or exudates can be obtained. In almost all of these situations, the materials examined have been exfoliated cells. Individual cell morphology rather than tissue structure has been used as diagnostic criterion.

Cutaneous tumors do not lend themselves readily to the study of exfoliated cells, since their surfaces are either intact, hyperkeratotic, or crusted. Several methods for obtaining smears from skin tumors have been reported, varying from impression smears and aspiration (needle) biopsy² to superficial curette abrasion.³ Wright stain, May-Grünwald-Giemsa, and various Papanicolaou modifications have been used for staining.⁴

Large-scale studies of the application of cytodiagnostic techniques to skin . . . [Full Text PDF of this Article]

Author Affiliations
Buffalo

From the Departments of Dermatology, Pathology, and Medical Illustration (Mr. William Payne, Photographer), Roswell Park Memorial Institute.

Footnotes
Supported in part by USPHS Grant C-2818.

Shown as a Scientific Exhibit of the Section on Dermatology at the 105 Annual Meeting of the American Medical Association, San Francisco, June 11-15, 1956.

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