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Report of a Case

HARRY L. ARNOLD, Jr., M.D.; I. L. TILDEN, M.D.

AMA Arch Derm. 1957;76(4):427-430.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The L. E. factor is not found exclusively in systemic lupus erythematosus. It has been reported in hemolytic anemia, multiple myeloma, leukemia, miliary tuberculosis, pernicious anemia, dermatitis herpetiformis, drug reactions to penicillin and hydralazine (Apresoline), diffuse systemic rheumatic disease, and diffuse progressive scleroderma.¹

Systemic lupus erythematosus is a protean disease, however, and may be manifested only by a single finding, such as fever, or albuminuria, during a part of its course. In many of the above instances it is difficult, and in a few it is impossible, to be sure that the obvious disease was not a manifestation of, or accompanied by, unrecognized systemic lupus erythematosus.

The present report concerns a case of typical diffuse progressive scleroderma in which, during nearly a year's close observation (including autopsy) not a single finding occurred to warrant even a suspicion that the disease was accompanied by systemic . . . [Full Text PDF of this Article]

Author Affiliations
Honolulu, Hawaii

Footnotes
Submitted for publication April 5, 1957.

Read before the staff meeting of the Straub Clinic, Feb. 11, 1957.

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