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LEONARD E. SAVITT, M.D.

AMA Arch Derm. 1957;76(6):780-782.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The author's successful clearing of lesions of necrobiosis lipoidica diabeticorum¹ by injections of hydrocortisone acetate prompted an 18-month clinical investigation into the effect of injecting hydrocortisone into other dermatologic lesions.

Several other investigators have reported their results following injection of hydrocortisone into skin lesions. Sullivan² found that lesions of sarcoidosis responded better to injections of hydrocortisone than to cortisone. Zachariae and Zachariae³ reported improvement of Dupuytren's contracture and Peyronie's disease after injections of hydrocortisone acetate. J. Graham Smith⁴ also reported 50% improvement in one case of necrobiosis lipoidica diabeticorum after the local injection of hydrocortisone and cited three other instances of similar improvement. In one case of localized myxedema reported by Forsey and Anhalt⁵ injections of hydrocortisone cleared the lesions after hyaluronidase had failed; in another case, hydrocortisone and hyaluronidase used simultaneously cleared lesions which had resisted them when used separately. Buchholz . . . [Full Text PDF of this Article]

Author Affiliations
Los Angeles

Footnotes
Received for publication April 9, 1957.

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