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INDUCED LOCALIZED ECZEMA
A. Rostenberg, Jr., M.D.
University of Illinois College of Medicine 1853 W. Polk St., Chicago, Ill.
AMA Arch Derm. 1957;76(6):791.
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To the Editor: I believe that the interesting report by Derbes and Caro, "Localized Eczema Induced by House Dust Extract Injections," which appeared in the June ARCHIVES deserves further comment. The authors do not clearly state just what they believe was the mechanism for the development of the patch of eczema; but they imply that the dermatitis arose because of the union of the antigen with its atopic antibody. This, if true, would be an important observation and would be relevant to the possible genesis of atopic eczema. Because the authors do not furnish an unambiguous interpretation of their findings, and because to me their findings are interpretable by quite another explanation, this letter is being written.
It is my opinion that the lesions seen arose because of the concomitant development of an eczematous type of delayed hypersensitivity to an ingredient in the house dust antigen. The development of a
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