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Treatment with Vitamin A Buccal Tablets; Report of Three Cases

J. HARVEY JOHNSTON, M.D.; SAMUEL J. ZAKON, M.D.

AMA Arch Derm. 1958;77(1):115.

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Past experience in the treatment of lichen planus involving the buccal mucosa has been very disappointing. In a recently published textbook of dermatology¹ the lack of an effective remedy for mucosal lichen planus is stressed as follows: "The management of inflamed lesions of lichen planus on the buccal mucosa is a particularly vexing and difficult problem. No topical therapy is of any regular value, and mouth lesions of lichen planus, especially those which become thickened and eroded, are possibly the most resistant manifestations of this disease."

Urbach² recently reported excellent improvement of severe oral lichen planus after the use of vitamin A buccal tablets using rather large doses (150,000 units three times a day). We wish to report our observations in three cases of lichen planus with oral lesions using a much smaller dosage with equally excellent results. Two of these cases were in men who . . . [Full Text PDF of this Article]

Author Affiliations
Chicago

Footnotes
Received for publication June 21, 1957.

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