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I. Mechanical Stimuli to the Skin; Inhibition of White Dermographism

WILLIAM B. REED, M.D.; ROBERT R. KIERLAND, M.D.; CHARLES F. CODE, M.D.

AMA Arch Derm. 1958;77(1):91-96.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

A series of studies has been made at the Mayo Clinic on vascular reactions seen in chronically inflamed skin. The studies reported in this paper were concerned with mechanical cutaneous stimulation and with inhibition of white dermographism.

Mechanical Stimuli to the Skin

A white reaction, or pallor, may occur when a blunt point is stroked with light pressure across normal skin. Blood is displaced temporarily from the superficial vessels of the skin, but the stroked portion becomes paler than the surrounding skin within 10 to 15 seconds. This zone of paleness, limited strictly to the sites of mechanical stimulation, suggested to Lewis¹ and to Müller² that this change was caused by contraction of the vessels responsible for cutaneous color and not to the passive contraction of arterioles that supply zones of skin more than a square millimeter or so in extent. Lewis . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn.

Footnotes
Received for publication June 12, 1957.

Fellow in Dermatology (Dr. Reed), Mayo Foundation; Section of Dermatology (Dr. Kierland) and Section of Physiology (Dr. Code), Mayo Clinic and Mayo Foundation. The Mayo Foundation, Rochester, Minn., is a part of the Graduate School of the University of Minnesota.

Portion of the essay that was awarded fourth prize in the annual essay contest of the American Dermatological Association, Inc., in 1956. Abridgment of portion of thesis submitted by Dr. Reed to the Faculty of the Graduate School of the University of Minnesota in partial fulfillment of the requirements for the degree of Master of Science in Dermatology.

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