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Case with Unusual Skin Lesions and Favorable Response to Amphotericin B Therapy

ROBERT G. CROUNSE, M.D.; AARON B. LERNER, M.D., Ph.D.

AMA Arch Derm. 1958;77(2):210-215.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Cryptococcosis is the name given to an infection having local and/or systemic lesions caused by the yeast-like organism Cryptococcus neoformans, formerly known as Torula histolytica. It is not a common disease in man. An exhaustive and admirable review of this topic was presented recently by Littman and Zimmerman,¹ who estimated that over 200 cases had been reported in the world literature up to 1956.

The most commonly involved site in human cryptococcosis is the central nervous system. The lungs are second in frequency. Presenting symptoms most often express these predilections. Cutaneous cryptococcosis is unusual. In the most recent compilation² a total of 37 cases was recorded, although isolated references to unpublished cases are found occasionally.

Some confusion arises in consulting the literature because of the following factors. Classification of the Cryptococcus organism is not exact. Much is still to be learned concerning its . . . [Full Text PDF of this Article]

Author Affiliations
New Haven, Conn.

Footnotes
Submitted for publication July 10, 1957.

Section of Dermatology, Department of Medicine, Yale University School of Medicine.

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