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Leukomelanoderma Subsequent to the Application of Monobenzyl Ether of HydroquinoneA Vitiligoid Reaction Observed in Colombia and Venezuela
ORLANDO CANIZARES, M.D.;
FABIO URIBE JARAMILLO, M.D.;
FRANCISCO KERDEL VEGAS, M.D.
AMA Arch Derm. 1958;77(2):220-223.
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The role of monobenzyl ether of hydroquinone as a cause of depigmentation has been known since the report of Oliver, Schwartz, and Warren1 in 1940. These authors studied 20 patients with a peculiar leukoderma localized to the hands and forearms, produced by a type of rubber gloves in which Agerite Alba had been used as an antioxidant. The leukoderma occurs primarily on the areas in direct contact with the causative agent but was also observed affecting the trunk and extremities. One of their patients was a Negro with a striking depigmentation of the abdomen, upper part of the thighs, and buttocks. The authors stated that this could not be explained except that it was probably due to rubbing sweat and water off his body. Sulzberger2 mentioned a Negro with a generalized vitiligoid depigmentation, almost resembling an albino.
The discovery of the properties of mono
. . . [Full Text PDF of this Article]
Author Affiliations
New York; Medellín, Colombia; Caracas, Venezuela
From the Department of Dermatology and Syphilology of the New York University Post-Graduate School (Dr. Marion Sulzberger, Chairman) and the Service of Dermatology and Syphilology of Bellevue Hospital (Dr. Frank C. Combes, Chief of Service).
Footnotes
Submitted for publication July 23, 1957.
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