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HENRY E. MICHELSON, M.D.

AMA Arch Derm. 1958;77(5):546-553.

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Erythema nodosum was recognized and described by many of the early leaders in dermatology. Erasmus Wilson, in 1842, gave to us a clinical description of the condition which cannot be improved upon today. The lesions and the accompanying constitutional symptoms of this disease shed no light upon its etiology. It was long considered to be either a form of or very closely allied to erythema multiforme, hence it was looked upon as belonging to the rheumatoid group of diseases. In more recent years doubt was cast upon the entity of erythema nodosum. Nodose lesions that could not be distinguished morphologically from those in the idiopathic cases were observed following the ingestion of certain drugs, such as bromides, and when the sulfonamides came into general use nodose cutaneous lesions were observed rather frequently, especially as a manifestation of intolerance to sulfathiazole. The most important doubt concerning . . . [Full Text PDF of this Article]

Author Affiliations
Minneapolis

Footnotes
Received for publication Dec. 27, 1957.

Read before the annual meeting of the MontrealQuebec Dermatological Society, Montreal, February, 1955.

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