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JACQUELINE WALKER, Ph.D.

AMA Arch Derm. 1958;78(2):153-156.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Morphologic variation in culture is not uncommon with some species of dermatophytes. It has been the basis of many reported new species, the names of which have subsequently passed into synonymy. Emmons¹ observed spontaneous variation in an old, single-spore culture of Microsporum gypseum growing on horn, and he was able to isolate from the strain six distinct and stable variants.

Smith² showed that variation in fungi could be induced by ultraviolet irradiation. Emmons and Hollaender,³ working with Trichophyton mentagrophytes and wavelengths of 2280 A. to 2950 A., showed that both mutant production and lethal effect were greatest in the region of wavelengths 2537 A. and 2650 A. They believed that these variants, because of their character and permanence, represented true genetical changes and could, therefore, be regarded as mutants.

Later Hollaender and Emmons⁴ showed that mutants in fungi could be produced by . . . [Full Text PDF of this Article]

Author Affiliations
London

Footnotes
Submitted for publication Jan. 2, 1958.

Mycological Reference Laboratory, Public Health Laboratory Service, London School of Hygiene and Tropical Medicine.

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