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GEORGE H. KOSTANT, M.D.; LOUISE C. KELCEC, M.T.

AMA Arch Derm. 1958;78(2):181-185.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The ideal serologic test for syphilis would be one which satisfies certain practical and logical criteria. It should give positive reactions with the serums of all patients with a syphilitic infection; it should give negative reactions with the serums of nonsyphilitic persons; furthermore, it should be relatively inexpensive and simply performed by the average hospital laboratory. Unfortunately, such an ideal test is not available. Theoretically, a test employing cultured pathogenic Nichols strain Treponema pallidum as an antigen could be expected to fulfill these criteria. To date, however, the cultivation of this micro-organism has never been realized, despite the efforts of Noguchi^1-3 and others. In an attempt to culture this treponeme Nelson⁴ devised a medium which is capable of maintaining the life of the virulent Nichols strain T. pallidum for as long as 14 days with a half-life of 6 to 8 days. Unfortunately, . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the Department of Dermatology and Syphilology of the New York University Post-Graduate Medical School (Dr. Marion B. Sulzberger, Chairman) and the Skin and Cancer Unit of the New York University Hospital.

Footnotes
Received for publication March 1, 1958.

Read before the Bronx Dermatological Society, Dec. 19, 1957, in a symposium held in memory of Dr. Charles R. Rein and entitled "Syphilis and Related Treponematoses in the World Today."

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