This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citation map  • Citing articles on HighWire  • Citing articles on Web of Science (57)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

A Study of the Role of Collagen Degeneration of the Dermis in the Production of Skin Cancer

BRUCE S. MACKIE, M.B., B.S., D.D.M.; VINCENT J. McGOVERN, M.D.

AMA Arch Derm. 1958;78(2):218-244.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The association of cutaneous malignancy with degenerative changes of the dermis, in areas exposed to the sun, is frequently observed. This has led us to inquire into the nature of the relationship which exists between the two conditions.

1. Physiological Considerations

As it is the intention of this paper to deal with conditions which arise from long-term exposure to solar radiation, it is necessary to consider certain physiological aspects bearing upon the main theme. The discussion will primarily involve responses to ultraviolet light, as other wavelengths seem to have no photobiological activity.

Classification of Skin Types.—The first point is our own division of humans into three main types, depending on the degree of pigment in their skin, although all variations in grade between these types occur (Fig. 1).

Type 1, the fair-complexioned person, has little or no natural (inherent) pigment . . . [Full Text PDF of this Article]

Author Affiliations
Sydney, New South Wales, Australia

Footnotes
Received for publication Jan. 16, 1958.

Dermatological Department (Dr. Mackie) and Fairfax Institute of Pathology (Dr. McGovern), Royal Prince Alfred Hospital.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?