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Prednisolone (Meti-Derm) as an Aerosol for Dermatoses
HARRY M. ROBINSON, SR., M.D.
AMA Arch Derm. 1959;79(1):103-105.
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| Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings. |
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Topical applications of hydrocortisone1 and, more recently, prednisone or prednisolone2-4 are widely used in the treatment of many types of dermatologic disease. A new vehicle for prednisolone (Meti-Derm) aerosol with 50 mg. of the steroid, isopropyl myristate, and Freon as a propellant, in a 150 gm. spray applicator, was made available to us for clinical study. A three-second spray delivers approximately 0.5 mg. of prednisolone.
Method
This series consisted of 79 patients with dermatologic disease, most commonly eczema of various types, including eczematous dermatitis. Patients were instructed to apply the aerosol to lesions in very short bursts of spray from a distance of 1 to 2 in. Examinations were made weekly and progress noted. No other therapy was used.
Results were graded as "excellent" if lesions involuted promptly and completely, "good" if response was somewhat slower or not complete, "fair" if some
. . . [Full Text PDF of this Article]
Author Affiliations
Baltimore
Footnotes
Submitted for publication July 9, 1958.
Clinical research supplies for this study were received from G. Kenneth Hawkins, M.D., of the Division of Clinical Research, Schering Corporation, Bloomfield, N. J.
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