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EDWARD V. ZEGARELLI, D.D.S.; FRANK G. EVERETT, D.M.D.; AUSTIN H. KUTSCHER, D.D.S.; JOHN GORMAN, M.D.; NORMAN KUPFERBERG, B.S.

AMA Arch Derm. 1959;80(1):59-65.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1935, Cannon¹ first called attention to a syndrome which he described as a white spongy nevus of the oral mucosa. A detailed review of the medical and dental literatire since that time has revealed 10 additional reports dealing with such a congenital disturbance of the oral mucous membranes. It has been variously termed "congenital leukeratosis of the oral mucosa" by Ludy and Shirazy,² "pachyderma oralis" by Kinney and Derifield,⁷ and "white folded gingivostomatosis" by Everett and Noyes,⁵ Orban and Wentz,⁶ and Darling and Fletcher.¹² Cooke^8,9 described two similar cases as "oral epithelial nevi." Lesions in the same patient in areas other than oral (dermal, vaginal, or rectal) have been documented in several of these reports.^5,11 A total of 15 cases have been actually observed and described in detail previously. Our review of the literature . . . [Full Text PDF of this Article]

Author Affiliations
New York

From the Division of Stomatology, School of Dental and Oral Surgery of the Faculty of Medicine, Columbia University, New York; the Department of Periodontology, University of Oregon Dental School, Portland, Ore., and the Institute of Cancer Research, Columbia University College of Physicians and Surgeons, New York.

Footnotes
Submitted for publication Nov. 9, 1958.

The following investigators assisted in this study: Drs. E. Shirazy, R. D. Kinney, R. S. Derifield, J. R. Trott, H. J. Noyes, H. E. Grupe, D. F. Mitchell, and B. Orban.

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