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A Clinical Note

KENNETH H. BURDICK, M.D.

AMA Arch Derm. 1959;80(5):587-589.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Iodine was first popularized as a surface and wound disinfectant shortly before the Civil War.

Since that time its rapid destruction of viruses, fungi, and spores has been repeatedly documented in the scientific literature. Certain inherent disadvantages, however, such as staining, tissue irritation, pain on application, offensive odor, and rapid inactivation by complexing with proteins and certain drugs, led to the introduction of a host of other disinfectants. None of these have, unfortunately, equaled iodine in range and rapidity of action.

Recently, several new complexes of iodine have been introduced. One, a complex of iodine with polyvinylpyrrolidone, a plasma expander, has been reported to be effective for surface disinfection and in treatment of eczematoid tinea.^1-3 Other new iodine complexes, the so-called ``iodophors'' have been available for the past few years. In these compounds, iodine has been complexed with various surfactants, to produce certain unique advantages. . . . [Full Text PDF of this Article]

Author Affiliations
Cleveland

From the Department of Dermatology (Dr. John R. Haserick, Chief), The Cleveland Clinic Foundation, and The Frank E. Bunts Educational Institute.

Footnotes
Submitted for publication June 6, 1959.

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