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The Effects of Hormone Administration and a Comparison with Adolescent Gland Function

J. GRAHAM SMITH, Jr., M.D.

AMA Arch Derm. 1959;80(6):663-671.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

A new technique for measuring the sebum excretion rate has been developed. It eliminates some of the errors inherent in other methods.

The amount of sebum excreted by the sebaceous gland has been shown to be influenced by several major factors. Miescher and Schönberg²⁰ have demonstrated that the amount of sebum excreted is dependent upon the size of the sebaceous gland. The larger the gland, the more sebum excreted, and vice versa. The size of the gland changes with age. Prior to puberty, in the human the sebaceous gland is small, and little sebum is excreted.^7,23 At puberty there is a great increase in sebum excretion which continues through adolescence.^14,16 There are conflicting reports as to whether adolescent males^7,16,28 or females⁵ have a higher level of sebum excretion, but aged women have a much lower level of sebum excretion than aged . . . [Full Text PDF of this Article]

Author Affiliations
Miami, Fla.

From the Division of Dermatology, Department of Medicine, University of Miami School of Medicine.

Footnotes
Submitted for publication Sept. 17, 1959.

This study was supported in part by a grant from the Bristol-Myers Company.

Dr. Smith is a special post-doctoral research fellow of the National Institute of Arthritis and Metabolic Diseases.

Read before the 79th Annual Meeting of the American Dermatological Association, Inc., Atlantic City, N.J., June 1, 1959.

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