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  Vol. 81 No. 4, April 1960 TABLE OF CONTENTS
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Benign Mixed Tumor of Melanocytes and Malpighian Cells

Melanoacanthoma: Its Relationship to Bloch's Benign Non-Nevoid Melanoepithelioma

YUTAKA MISHIMA, M.D.; HERMANN PINKUS, M.D.

AMA Arch Derm. 1960;81(4):539-550.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1927 Bloch1 described benign non-nevoid melanoepithelioma of the skin and subdivided it into two types. Type I consists of a mixture of basal cells, prickle cells, and highly dendritic melanocytes. Type II is composed mainly of deeply pigmented small cells of basal type.

Review of Literature

Since Bloch's time many authors have referred to these tumors under a bewildering variety of names and offered contradictory interpretations of their nature and classification (Table 1). This confusion can be traced to several factors in Bloch's original publication. Bloch was one of the exponents of the thesis that nevus cells are modified melanocytes, and that epidermal melanocytes are modified basal cells. Therefore, when he found pigmented epidermal tumors without the formation of nevus cells, he called them "non-nevoid" in distinction from pigmented nevus cell tumors. He made no distinction between lesions consisting of pigmented Malpighian cells without dendritic melanocytes (Type II) . . . [Full Text PDF of this Article]


Author Affiliations

Detroit

From the Departments of Dermatology, Wayne State University College of Medicine and Detroit Receiving Hospital, and the Detroit Institute of Cancer Research.


Footnotes

Submitted for publication July 7, 1959.

Abridgement of a portion of a thesis submitted by Dr. Mishima to the Faculty of the Postgraduate School of Medicine, University of Tokyo, in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Dermatology and Syphilology.

Supported in part by research grant RG-4435 and C-2072 from the National Institutes of Health, U.S. Public Health Service, and in part by research contract DA-49-007-MD-584 from the Research and Development Division, Office of the Surgeon General, Department of the Army.



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