This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

M. BARRY KIRSCHENBAUM, M.D.; ROGER W. PEARSON, M.D.; ALLAN L. LORINCZ, M.D.

AMA Arch Derm. 1960;81(4):561-564.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The cutaneous manifestations of tuberculosis can be grouped into two categories: (1) those in which actively multiplying tubercle bacilli are present in the lesions, and (2) those, the tuberculids, in which tubercle bacilli or their products embolize to the skin from some active, but at times obscure focus of the disease. In tuberculids, the embolized bacilli do not long remain viable, apparently because of the intense tissue reaction elicited by their presence in the skin.^1,2 Two well-defined types of tuberculids are papulonecrotic tuberculid and erythema induratum. In this report we present evidence that the extreme tuberculin sensitivity which characterizes these tuberculids³ can best be demonstrated with old tuberculin (O.T.) rather than with more purified derivatives such as the purified protein derivative (PPD).

It is of interest that Darier⁴ in 1896 introduced the concept of tuberculid before knowledge about tuberculin skin testing was developed shortly after the turn . . . [Full Text PDF of this Article]

Author Affiliations
Chicago

From the Section of Dermatology, Department of Medicine, University of Chicago.

Footnotes
Submitted for publication July 13, 1959.

Read before the Section on Dermatology at the 108th Annual Meeting of the American Medical Association, Atlantic City, N.J., June 10, 1959.

This study was supported in part by a grant from the Public Health Service, National Institute of Allergy and Infectious Diseases, Grant No. E-1444(C3) and in part by a grant from the A. B. Kuppenheimer Research Endowment Fund.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?