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Erythema Annulare Centrifugum, Generalized Pigmentation and Breast Hypertrophy

WALTER B. SHELLEY, M.D., Ph.D.; HARRY J. HURLEY, M.D., D.Sc. (Med.)

AMA Arch Derm. 1960;81(6):889-897.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

For the past year we have studied a young woman with a unique triad of findings: enormous breast hypertrophy, generalized melanoderma, and, finally, thousands of pruritic polycylic bands undergoing continuous migration over the skin surface. We have encountered nothing of this kind in our clinical experience or in the literature. Intensive investigative studies disclosed the presence of an autoallergic state. The patient proved to have specific circulating autoantibodies to her own cystic breast tissue. In addition, her serum showed a strongly positive L.E. phenomenon. Accordingly it is our wish to record and to attempt to interpret these clinical observations and laboratory studies.

Report of a Case

The patient, a 26-year-old white woman, was first seen by us in October, 1958.^* At that time she presented the three problems (Figs. 1, 2, 3) of breast enlargement, melanoderma, and gyrate migratory bands.

Although she had had purpura and an attack of poison . . . [Full Text PDF of this Article]

Author Affiliations
Philadelphia

Present address: Department of Dermatology, Hahnemann Medical College, Philadelphia (Dr. Hurley).; From the Department of Dermatology, University of Pennsylvania School of Medicine, Philadelphia.

Footnotes
Submitted for publication Aug. 14, 1959.

This work was supported by Army Research Contract No. DA-49-007-MD-154.

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