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  Vol. 82 No. 3, September 1960 TABLE OF CONTENTS
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Degenerative Collagenous Plaques of the Hands

JAMES W. BURKS, M.D.; LOUIS J. WISE, Jr., M.D.; WALLACE H. CLARK, Jr., M.D.

Arch Dermatol. 1960;82(3):362-366.

Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

This report describes the clinical and pathologic features of a series of patients we have observed with linear, firm plaques of the medial and lateral aspects of the hands. Five illustrative cases are presented. The lesions are bilateral and symmetrical and are situated at the juncture of the palmar and dorsal skin. Histologically, the process is characterized by a rather distinctive deposition of dense collagen and elastic tissue, involving most of the reticular dermis but usually sparing the papillary dermis and subcutis.

The condition is chronic, essentially asymptomatic, and slowly progressive. Our patients could not date the exact onset of their lesions but had noticed slow development over a 5- to 15-year period. The only symptom mentioned by any of the patients has been stiffness resulting from advanced involvement of the flexor creases. In the fully developed case, both hands are symmetrically involved. A firm plaque extends from near the . . . [Full Text PDF of this Article]


Author Affiliations

New Orleans

Markle Scholar in Medical Science (Dr. Clark).

From Division of Dermatology, Department of Medicine and the Department of Pathology, Tulane University School of Medicine, New Orleans, La.


Footnotes

Submitted for publication Dec. 28, 1959.



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