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2,5-DIHYDROXYPHENYLPYRUVIC ACID AND COLLAGEN DISEASES
A. R. Williamson, M.D.
Rock Island, Ill.
Arch Dermatol. 1960;82(3):428.
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To the Editor:
In March a paper was published in the A.M.A. ARCHIVES OF DERMATOLOGY on the subject of defective protein metabolism in collagen diseases (Tye, M. J., et al.: 2,5-Dihydroxyphenylpyruvic Acid and Collagen Diseases, A.M.A. ARCH. DERMAT. 81:447, 1960). It described the failure of the authors to confirm the presence of urinary 2,5-dihydroxy-phenylpyruvic acid as originally described by Nishimura.
However, by using a slightly modified technique, a group of French investigators recently confirmed the Japanese findings (Bulletin de la Société française de dermatologie, No. 4, October, 1959).
I feel that an interest in this line of research should be kept alive.
Yours truly
. . . [Full Text PDF of this Article]
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