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Necrobiosis Lipoidica Diabeticorum in the Nondiabetic

TROY G. ROLLINS, M.D.; R. K. WINKELMANN, M.D.

Arch Dermatol. 1960;82(4):537-543.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

During the past 25 years necrobiosis lipoidica diabeticorum (N.L.D.), as described by Oppenheim and Urbach and reviewed by others,^{1,3,6-13,16,20,24} has come to be recognized as a distinct entity. The disease is a chronic granulomatous process. Its lesions, which occur predominantly on the lower extremities, consist of irregular, sclerotic plaques with erythematous, violaceous borders and yellowish centers.

A condition described in 1936¹⁴ and presented as a separate entity in 1948 by Miescher and Leder is known as Miescher's granulomatosis disciformis chronica et progressiva (Miescher's G.D.C. et P.). This is a dermatologic condition presenting discoid plaques that have an erythematous, violaceous border and a central yellowish, atrophic center with telangiectasis coursing over its surface. It is indistinguishable clinically from N.L.D., and shows some histologic similarities to it, but usually is not associated with diabetes or tuberculosis.^2,5,23

We have studied in the diabetic and nondiabetic the clinical and histopathologic features . . . [Full Text PDF of this Article]

Author Affiliations
Rochester, Minn.

Fellow in Dermatology, Mayo Foundation (Dr. Rollins); Section of Dermatology (Dr. Winkelmann), Mayo Clinic and Mayo Foundation. The Mayo Foundation is a part of the Graduate School of the University of Minnesota.

Footnotes
Submitted for publication Dec. 28, 1959.

Abridgment of portion of thesis submitted by Dr. Rollins to the Faculty of the Graduate School of the University of Minnesota in partial fulfillment of the requirements for the degree of Master of Science in Dermatology; abridgment of paper awarded third prize in essay contest sponsored by the American Dermatological Association, November, 1958.

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