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S. W. BECKER, Jr., M.D.; B. BRENNAN, M.D.; PAUL K. WEICHSELBAUM, M.D.

Arch Dermatol. 1960;82(6):857-864.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Paget's disease, mammary and extramammary, has been the subject of controversy for more than 4 score years. The meticulous study of Bennett¹ has demonstrated that Paget's disease of the nipple is always associated with an adenocarcinoma in the underlying breast. No such comprehensive investigation has been done on extramammary Paget's disease. This condition is most commonly seen in the genital, perianal, and axillary regions. Two entities have been described. Some patients have a primary carcinoma of an underlying organ (anal canal, prostate)² with lymphatic extension of the tumor to the epidermis. In the other type, which this paper will discuss, there is no underlying carcinoma. At present there are 2 hypotheses regarding pathogenesis. Woodruff³ and Woodruff and Richardson⁴ feel that vulvar Paget's disease is a carcinoma of epithelial origin, whereas Weiner⁵ and more recently, Dockerty and Pratt,⁶ support the thesis that Paget's cells migrate . . . [Full Text PDF of this Article]

Author Affiliations
Chicago

The Department of Dermatology, University of Illinois Medical School, Chicago.

Footnotes
Dr. Weichselbaum died on Feb. 19, 1960.

Submitted for publication June 2, 1960.

Read before the 80th Annual Meeting of the American Dermatological Association, Inc., Boca Raton, Fla., April 8-12, 1960.

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