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Pathologic Dynamics of Human Hair LossI. Telogen Effluvium
ALBERT M. KLIGMAN, M.D., Ph.D.
Arch Dermatol. 1961;83(2):175-198.
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This study concerns the behavior of the human follicle under stresses which cause temporary loss of hair. Many different agencies cause hair shedding.1 For some years now, I have been watching what happens to the follicle in a variety of natural and experimental alopecic conditions. Out of these observations has grown a biological generalization, the presentation of which is the main business of this essay.
To grasp the meaning of this generalization, requires a thorough understanding of the hair cycle, and, in particular, catagen, that brief epoch during which a growing follicle (anagen) becomes transformed into a resting one (telogen). The prelude to the present theme is to be found in a previous paper dealing with the dynamics of human catagen.2 Further important readings are Montagna's3 analyses of hair cycle mechanics, and a recent study of catagen by Ellis and Moretti.4 The dynamics of change in
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
From the Department of Dermatology of the University of Pennsylvania Medical School, and the Hospital of the University of Pennsylvania, Philadelphia.
Footnotes
Submitted for publication Aug. 1, 1960.
This research was supported in part by Public Health Service Grant PHS 2G-62.
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