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Acrosclerotic Type

MANUEL O. JAFFE, M.D.; R. K. WINKELMANN, M.D.

Arch Dermatol. 1961;83(3):402-413.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Scleroderma in children is uncommon, and while localized cutaneous forms of the disease occur more frequently among them, cases of generalized scleroderma are especially rare. Two clinical variants of generalized scleroderma have been described: diffuse scleroderma and acrosclerosis.¹ Acrosclerosis was first described by Hutchinson,² and Sellei³ championed its status as a disease sui generis. O'Leary and Waisman⁴ stressed the importance of vasomotor abnormalities in acrosclerosis and its good prognosis as compared to that of diffuse scleroderma. Acrosclerosis involves predominantly the skin of the face, upper part of the chest, hands, forearms, and occasionally the feet. A vasospastic (Raynaud's) phenomenon is associated with the sclerosis. Varying degrees of systemic involvement may occur, the gastrointestinal, pulmonary, and cardiorenal systems being most frequently affected.

The early dermatologic literature pertaining to scleroderma^5-8 in children is confusing because many cases presented as diffuse scleroderma would be, in our opinion, more . . . [Full Text PDF of this Article]

Author Affiliations
ROCHESTER, MINN.

Fellow in Dermatology, Mayo Foundation (Dr. Jaffe); Section of Dermatology (Dr. Winkelmann); Mayo Clinic and Mayo Foundation.

Footnotes
Submitted for publication Sept. 16, 1960.

The Mayo Foundation is a part of the Graduate School of the University of Minnesota.

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