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Chronic Urticaria Due to Mold HypersensitivityA Study in Cross-Sensitization and Autoerythrocyte Sensitization
WALTER B. SHELLEY, M.D., Ph.D.;
RALPH FLORENCE, M.D.
Arch Dermatol. 1961;83(4):549-558.
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Chronic urticaria, perhaps more than other dermatoses, challenges the physician and patient to find its cause. At times this challenge is met with ease, e.g., in the patient with dermographism, a penicillin reaction, cold allergy, or mastocytosis. Yet at other times the hives remain completely mysterious and capricious despite a wearying series of trial diets, environmental changes, skin tests, and psychotherapy. The causes of urticaria seem legion, and in some patients the elimination of 1 etiologic suspect may be followed by the appearance of 10 new ones. We are therefore prompted to record our studies of a patient with chronic urticaria due to a hypersensitivity so extreme as to enable us to view the disease, as it were, under a "clinical microscope." His exquisite sensitivity permitted us to discern a common causal thread extending throughout his entire history of hives. Thus, it was possible to observe a single basic cause,
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
Department of Dermatology, University of Pennsylvania School of Medicine.
Footnotes
Submitted for publication Nov. 14, 1960.
This study was conducted under the sponsorship of the Commission on Cutaneous Diseases of the Armed Forces Epidemiological Board and was supported by the Office of the Surgeon General, Department of the Army.
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