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WILLIAM M. COON, M.D.; FRANZ HERRMANN, M.D.; LEONA MANDOL, B.S.

Arch Dermatol. 1961;83(4):619-626.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In a recent paper¹ we reported on the acid number (A.N.) of the ether-soluble substances collected from the skin of patients with psoriasis in comparison with the values obtained in healthy subjects. Collections were made from both the intact skin surface and from the base of the stratum corneum. Access to this deeper level, the "barrier zone," or "stratum conjunctum," of Szakall, was gained by using Scotch cellophane tape to strip away the outer horny layers, i.e., the "stratum disjunctum."^2-5 In earlier studies, the acid number of the lipids collected from the barrier zone (B.Z.) in healthy subjects was found to be lower than the acid number of the samples collected from the unstripped skin surface (S.S.). In psoriatic patients, however, there was a quite constant reversal of this relationship; that is, we found the acid number at the barrier zone to be higher than at the skin . . . [Full Text PDF of this Article]

Author Affiliations
NEW YORK

From the Department of Dermatology and Syphilology of the New York University Post-Graduate Medical School (Dr. Marion B. Sulzberger, Chairman) and the Skin and Cancer Unit of the University Hospital.

Footnotes
Submitted for publication Aug. 8, 1960.

This investigation was supported by Grant #DA-49-007-MD-753 from the U.S. Army Medical Research and Development Command.

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