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Observations on 2 Patients Treated with Brazilian Regimen

MICHAEL SCHIFF, M.D.

Arch Dermatol. 1961;84(1):103-108.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Introduction

At the present time corticosteroids are generally considered the best agents for controlling pemphigus.¹ Morbidostasis often necessitates the use of high doses for long periods, causing inevitable dangers inherent in the therapy itself.^1,2 The risks of such treatment are fully justified in pemphigus vulgaris, for without corticosteroids a rapid malignant progression almost invariably ensues.³

Pemphigus erythematosus, however, tends to run a relatively slow and benign course^4,5 and shows a capricious response to corticosteroids.^2,6 In this disease the complications of corticosteroid therapy may outweigh the benefits. Thus, a safe and effective alternative form of management would be highly desirable.

Shortly after the publication of Counter's favorable report⁷ on the Brazilian treatment of fogo selvagem with Jamarsan, the problem of therapy in 2 patients with typical pemphigus erythematosus arose here. Since there is no apparent clinical or histopathologic difference between pemphigus erythematosus and the "frustre" . . . [Full Text PDF of this Article]

Author Affiliations
HANOVER, N.H.

From the Department of Dermatology, Hitchcock Clinic.

Resident in Dermatology, Hitchcock Clinic (Dr. Schiff).

Footnotes
Submitted for publication Jan. 24, 1961.

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