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A Histologic and Serologic Study

LEONARD W. BUNCH, M.D.; JOE C. TILLEY, M.D.

Arch Dermatol. 1961;84(1):79-86.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Approximately 100 years ago Gibert first described the macular form of pityriasis rosea, and Bazin added a description of the circinate variety. Percival, in 1931, gave a good review of the subject.¹

Much has been written concerning the etiology of pityriasis rosea. Etiologies that have been suggested are fungus infection, staphylococcal, and streptococcal infections of the tonsils with autointoxication, a toxic exanthem from a gastrointestinal tract infection, and psychogenic and neurogenic concepts. Viral etiology has been postulated, but viral cultures have been unsuccessful. Wile² may have reproduced an aberrant form of the disease by experimental transmission. The most widely accepted etiology is that of a weakly infectious disease, probably of viral origin.⁸

There has been a sparsity of reports concerning the histopathology of the disease. Pels³ cites Kyrle's findings of "mild inflammatory reaction in the epithelium (spongiosis) including intraepithelial vesiculation." Also, he gives a more detailed . . . [Full Text PDF of this Article]

Author Affiliations
NEW ORLEANS

From the Independent Dermatology Service Charity Hospital (Dr. Bunch; V. Medd Henington, M.D., Chief) and the Louisiana State University Dermatology Service, Charity Hospital (Dr. Tilley; Barrett C. Kennedy, M.D., Chief).

Footnotes
Submitted for publication Jan. 10, 1961.

Presented before the Louisiana Dermatological Society, New Orleans, Sept. 18, 1960.

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