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Report of a Case

FRANCISCO KERDEL-VEGAS, M.D.; JACINTO CONVIT, M.D.; JOSE M. SOTO, M.D.

Arch Dermatol. 1961;84(2):248-255.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Granuloma inguinale (granuloma venereum, donovanosis), a disease of the skin and subcutaneous tissues, usually of the genital region, and seen mainly among the darkskinned races, is still endemic in some parts of the world including southern United States. The etiology, epidemiology, diagnosis, differential diagnosis, and clinical course have been well reviewed by Greenblatt and associates¹ and Thambiah.²

Penicillin has proved ineffective, and nonspecific treatment has been generally disappointing and punctuated by relapses. Until the advent of streptomycin, dissemination to other parts of the body, with prolonged disability and even death, resulted directly or indirectly from secondary spread of the lesions from the primary focus. Medina and Alarcón³ reported a fatal case in a white woman of granuloma inguinale with large granulomatous ulcerations on the external genitals, and invasion of vaginal mucosa and uterine cervix. Despite antibiotic treatment, ulcerous lesions on the left leg and an intestinal fistula . . . [Full Text PDF of this Article]

Author Affiliations
CARACAS, VENEZUELA

From the Department of Dermatology, Vargas Hospital (Dr. Kerdel-Vegas, Assistant Professor; Dr. Convit, Associate Professor; and Dr. Soto, Resident Physician).

Footnotes
Submitted for publication Jan. 30, 1961.

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