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P. C. ANDERSON, M.D.

Arch Dermatol. 1961;84(2):316-317.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

In 1951 Cornbleet described a minor cutaneous defect, a red transverse stripe or groove across the nose.^1,2 The groove is 1-3 mm. wide and about 1 mm. deep, is continuous, and lies across the nose, just proximal to the alae nasi (Fig. 1). This paper reports 2 families in which 14 examples of the transverse nasal groove were found. The pattern of inheritance suggests that the trait is due to a single dominant gene.

Pedigree I shows that whenever verification can be made affected individuals have an affected parent. The nasal groove was associated with hyperelasticity of the joints in 4 cases. Otosclerotic deafness at an early age occurred in I-3; II-2, and III-7. Diabetes was present in II-3. No allergic rhinitis was found. The irregular genetic pattern seen in Pedigree II is best explained by the assumption that, as in Pedigree I, the trait is caused by a . . . [Full Text PDF of this Article]

Author Affiliations
ANN ARBOR, MICH.

From the Department of Dermatology (Dr. Arthur C. Curtis, Chairman) of the University of Michigan Medical Center.

Footnotes
Submitted for publication March 29, 1961.

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