This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (9)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

X. VILANOVA, M.D.; R. CASTILLO, M.D.; J. PINOL AGUADE, M.D.

Arch Dermatol. 1961;84(4):603-606.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Mast cell disease has seldom been associated with hemorrhagic accidents^1,2 or with coagulation abnormalities such as prolonged coagulation time, prolonged bleeding time, abnormal prothrombin concentration in tolerance test for heparin. Some of the above anomalies have been explained by an associated liver alteration³; others by the presence in plasma of inhibitors of the coagulation process.^4-9 In most instances, however, the laboratory findings have been minimal or the cases did not show clinical manifestations.

Urbach, Bell, and Jacobson¹⁰ by local friction on cutaneous lesions of urticaria pigmentosa demonstrated a temporary increase of blood heparin in their cases. Berlin¹¹ found in blood obtained from a cutaneous lesion an abnormal coagulation process.

We have had the opportunity to observe a child with nodular urticaria pigmentosa with severe bleeding from the biopsy site, who required a whole blood transfusion. The coagulation defect was due to the presence of a . . . [Full Text PDF of this Article]

Author Affiliations
BARCELONA, SPAIN

Department of Dermatology (Drs. Vilanova and Piñol Aguadé) and Department of Hematology (Dr. Castillo), Faculty of Medicine, University of Barcelona.

Footnotes
Submitted for publication May 9, 1961.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?