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John Dougherty, M.D.; Maurice J. Costello, M.D.

Arch Dermatol. 1961;84(5):868-873.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Diagnosis: Darier's Disease. Presented by DR. S. M. PECK.

History.—

A 41-year-old female. Skin eruption of about 35 years' duration. This patient has been under observation continuously since 1942. She has always noted that exposure to strong sunlight would cause a flare of her skin eruption on exposed areas. In 1952, after a summer vacation, there was a marked exacerbation of lesions with appearance on the face suggestive of L.E.

Family History.—

A niece also had Darier's disease.

Laboratory Findings.—

Essentially normal including blood cholesterol, blood sugar, etc. Vitamin A levels taken when she was first seen with the method then available showed inadequate response to ingestion of vitamin A in fairly large doses. Skin biopsy was compatible with the diagnosis of Darier's disease.

Clinical Course.—

She has been under continuous vitamin A therapy in doses of 150,000 units a day per os, and at times this had to be . . . [Full Text PDF of this Article]

Footnotes
Submitted for publication May 11, 1961.

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