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PorokeratosisA Disease of Epidermal Eccrine-Sweat-Duct Units
THOMAS S. SAUNDERS, M.D.
Arch Dermatol. 1961;84(6):980-988.
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Historical Considerations
Porokeratosis is a disease characterized by sharply circumscribed, kerato-atrophic areas in the midst of unchanged skin occurring in sites of predilection. The lesions are usually multiple—rarely single; familial incidence is frequent, with males being affected twice as often as females.
Although Majocchi1 was the first to recognize porokeratosis as an entity (1883), naming it "linear and hystrix ichthyosiform dermatosis," his successor Mibelli described the condition in such detail (1893) that it bears his designation (porokeratosis). Independently of Mibelli, Respighi described it and named it "hyperkeratose figuree centrifuge atrophicante." Gilchrist, in the United States, emphasized the hereditary aspects of the dermatosis.1
Porokeratosis is a rare disease, yet Bopp2 encountered 16 cases in one year. Although there are numerous reports of individual cases in the literature, detailed and exhaustive studies of the disease are nevertheless lacking.
In their report published in 1943, Bloom and Abramowitz3 prophesied
. . . [Full Text PDF of this Article]
Author Affiliations
PORTLAND, ORE.
Clinical Professor of Dermatology, University of Oregon Medical School, Portland.
Footnotes
Submitted for publication July 21, 1961.
Read before the 81st Annual Meeting of the American Dermatological Association, Inc., Tucker's Town, Bermuda, June 16, 1961.
This investigation was supported (in part) by a U.S. Public Health Service research grant, E-3102(C1) from the National Institutes of Allergy and Infectious Disease.
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