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MARK ALLEN EVERETT, M.D.

Arch Dermatol. 1961;84(6):997-998.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The occurrence of carcinoma in areas of vitiligo is extremely rare. Its occurrence has never been recorded at the University of Oklahoma where an average of 200 new skin cancers a year are seen. Some protection against ultraviolet irradiation other than melanin must exist in these patients. Finsen¹ as early as 1900 suggested that the development of hyperkeratosis might afford protection. Lovisatti,² Guillaume,³ and Wirth⁴ later demonstrated the increased tolerance to ultraviolet light in vitiliginous and other patients. In 1930, Miescher⁵ showed microscopically the hyperkeratosis which occurs upon exposure to ultraviolet light. Comparative measurements of the keratin response in vitiliginous and pigmented areas have never been recorded. Accordingly, the following study was undertaken.

Method

Seven patients with vitiligo were studied. All presented symmetrical depigmentation of the extremities. In each patient, an erythema dose of ultraviolet light from a hot quartz mercury vapor lamp was administered . . . [Full Text PDF of this Article]

Author Affiliations
OKLAHOMA CITY

Department of Dermatology, University of Oklahoma School of Medicine. This work was supported by an American Cancer Society Institutional Grant.

Footnotes
Submitted for publication July 31, 1961.

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