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The Biology of Experimental Human Cutaneous Moniliasis (Candida Albicans)
HOWARD I. MAIBACH, M.D.;
ALBERT M. KLIGMAN, M.D.
Arch Dermatol. 1962;85(2):233-257.
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There has been no want of zeal in writing about moniliasis. Physicians seem endlessly fascinated by this disease and have constructed a mountainous literature as a monument to their interest. One would be greatly deceived if he were to think that this literary effusion signified a near complete knowledge of the disease process. On the contrary, there is a great lack of information on the dynamics of infection, the host-parasite relationship, and even so simple a thing as the histopathology. Current concepts derive almost entirely from gross clinical observation. Keen observation alone is insufficient to penetrate deeply into the mystery of the disease process and, indeed, has not even established firm diagnostic rules. In trying to evaluate the many things that have been said about moniliasis, one is plagued by doubts that the disease was correctly labeled in the first place. Certain expressions of the disease are unmistakable, but what
. . . [Full Text PDF of this Article]
Author Affiliations
PHILADELPHIA
From the Department of Dermatology, University of Pennsylvania School of Medicine.
Footnotes
Submitted for publication Aug. 21, 1961.
This investigation was carried out during the tenure of a postdoctoral fellowship, held by Dr. Maibach, from the Division of General Medical Sciences, United States Public Health Service.
This study was conducted in part under the sponsorship of the Commission on Cutaneous Diseases of the Armed Forces Epidemiological Board and was supported by the Office of the Surgeon General, Department of the Army.
This paper won first prize in the American Dermatological Association Essay Contest and was read before the 81st Annual Meeting of the American Dermatological Association, Inc., Tucker's Town, Bermuda, June 16, 1961.
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