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WILLARD C. PETERSON, JR., M.D.; MUHARREM GOKCEN, M.D.

Arch Dermatol. 1962;86(6):783-787.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

The relationship between systemic lupus erythematosus (S.L.E.) and chronic discoid lupus erythematosus (C.D.L.E.) has not been investigated adequately. In the past there has been a tendency of some to consider C.D.L.E. and S.L.E. as somewhat separate diseases. However, in recent years there appears to be more evidence clinically, to consider these 2 conditions as different manifestations of the same disease.¹ While the lupus erythematosus (L.E.) cell test is positive in many S.L.E. patients, it is almost uniformly negative in C.D.L.E.^2,3 The L.E. factor responsible for the L.E. cell formation is one of the numerous autoantibody-like factors present in the sera of S.L.E. patients which are directed against the nuclei. Detection of the L.E. factors by using the L.E. cell-formation methods does not appear to be sensitive enough for 2 major reasons: First the L.E. cell formation is a complex event involving in vitro phagocytic activity of white blood . . . [Full Text PDF of this Article]

Author Affiliations
MINNEAPOLIS

Medical Fellow (Dr. Peterson), Division of Dermatology, Department of Medicine, University of Minnesota Hospital.

Medical Fellow Specialist (Dr. Gokcen), Department of Medicine, University of Minnesota Hospitals.

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