This Article  • References  • Full text PDF  • Send to a friend  • Save in My Folder  • Save to citation manager  • Permissions  Citing Articles  • Citing articles on HighWire  • Citing articles on Web of Science (3)  • Contact me when this article is cited  Related Content  • Similar articles in this journal  Social Bookmarking   What's this?

Prophylactic Use With Particular Reference to Nickel Hypersensitivity

ALEXANDER A. FISHER, MD

Arch Dermatol. 1964;89(6):841-843.

	Since this article does not have an abstract, we have provided the first 150 words of the full text PDF and any section headings.

Barrier creams and protective ointments have proved to be of rather limited value in protecting the skin against irritants and sensitizers. For the past year it has been found that a film formed by spraying the skin with topical aerosol dexamethasone (Decadron) spray^* is effective in preventing dermatitis in individuals who would otherwise manifest allergic eczematous contact dermatitis from nickel-plated objects. A 90-gm tube of this spray contains 10 mg of dexamethasone; isopropyl myristate; and Freon propellants: trichloromonofluromethane and dichlorodifluoromethane.

According to the manufacturer each second of spray at 6 inches distance dispenses 0.75 mg of dexamethasone, a synthetic analogue of hydrocortisone.

The isopropyl myristate in this spray is a synthetic fatty oily compound which acts as a residual film after the Freon has evaporated. This fatty acid ester is used in many cosmetics as a lubricant and skin emollient in 2% to 10% concentration. The film formed by the . . . [Full Text PDF of this Article]

Author Affiliations
WOODSIDE, LI, NY

From the Department of Dermatology, New York University Schools of Medicine and The Skin and Cancer Unit, University Hospital, New York.

Footnotes
Read before the Symposium of Industrial Dermatoses, American Academy of Dermatology, Chicago, Dec 3, 1963.

CiteULike    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter     What's this?