Familial Benign Chronic Pemphigus. Presented by DRS. RAFAEL ANDRADE and HERBERT GOLOMB.
A 32-year-old man of Italian ancestry had "water blisters" on the chest 16 years ago. The condition cleared then and reappeared ten years ago. Since then there has been tendency to recurrences in the summertime and tendency to clearing during winter. The patient's father, his paternal grandmother, and a brother have a similar condition on the chest and back.
Examination when first seen showed crusted, moist, circinate, and gyrate plaques of process on the chest. That process consisted of tiny vesicles on erythematous bases at the periphery with erythema and scaling in the center.
Conventional histologic examination of the lesions and cytodiagnosis (Tzanck test) confirmed the clinical impression of familial benign chronic pemphigus (See Fig 1-3 and legends thereto.)
By way of treatment, the patient was given a tetracycline by mouth (250 mg four times daily), and an
. . . [Full Text PDF of this Article]