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RE: "INDUSTRIALLY ACQUIRED PORPHYRIA"
Franklin Pass, MD;
Walter G. Larsen, MD
University of Oregon Medical School 3181 SW Sam Jackson Park Rd Portland, Ore 97201
Arch Dermatol. 1965;91(1):93.
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To the Editor:
"Industrially Acquired Porphyria" by Bleiberg et al, ARCHIVES OF DERMATOLOGY1 is a significant contribution to the intriguing problem of acquired porphyria. We object to the authors' terminology and the lack of quantitative porphyrin data.
The eponym, "Watson-Schwartz test," is commonly associated with the detection and differentiation of urinary urobilinogen and porphobilinogen by the addition of Ehrlich's reagent and chloroform. Drs. Watson and Schwartz2 have described a qualitative test for urinary uroporphyrin, but this is not generally referred to by eponym. Therefore, when the authors determine uroporphyrin by the "Watson-Schwartz method," it is difficult to know which method is used. This is important to the reader, because the determination of porphobilinogen is of little or no value as a screening test for cutaneous porphyria.
The diagnosis and classification of porphyria is a complex problem and depends directly on quantitative assessment of urine and stool porphyrins. Without
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